منابع مشابه
Conductance-Based Integrate and Fire Models
A conductance-based model of Na+ and K+ currents underlying action potential generation is introduced by simplifying the quantitative model of Hodgkin and Huxley (HH). If the time course of rate constants can be approximated by a pulse, HH equations can be solved analytically. Pulse-based (PB) models generate action potentials very similar to the HH model but are computationally faster. Unlike ...
متن کاملOn conductance-based neural field models
This technical note introduces a conductance-based neural field model that combines biologically realistic synaptic dynamics-based on transmembrane currents-with neural field equations, describing the propagation of spikes over the cortical surface. This model allows for fairly realistic inter-and intra-laminar intrinsic connections that underlie spatiotemporal neuronal dynamics. We focus on th...
متن کاملHardware computation of conductance-based neuron models
We review di4erent applications of silicon conductance-based neuron models implemented on analog circuits. At the single-cell level, we describe a circuit in which conductances are programmed to simulate various Hodgkin–Huxley type models; integrated in a hardware/software system, they provide a simulation tool; an illustrative example is the simulation of bursting neurons of the thalamus. At t...
متن کاملConductance-Based Neuron Models and the Slow Dynamics of Excitability
In recent experiments, synaptically isolated neurons from rat cortical culture, were stimulated with periodic extracellular fixed-amplitude current pulses for extended durations of days. The neuron's response depended on its own history, as well as on the history of the input, and was classified into several modes. Interestingly, in one of the modes the neuron behaved intermittently, exhibiting...
متن کاملModifying spiking precision in conductance-based neuronal models.
The temporal precision of a neuron's spiking can be characterized by calculating its "jitter," defined as the standard deviation of the timing of individual spikes in response to repeated presentations of a stimulus. Sub-millisecond jitters have been measured for neurons in a variety of experimental systems and appear to be functionally important in some instances. We have investigated how modi...
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ژورنال
عنوان ژورنال: Scholarpedia
سال: 2006
ISSN: 1941-6016
DOI: 10.4249/scholarpedia.1408